People with severe mental illness (SMI) are at risk of chronic physical health conditions. However, physical health screening for this patient cohort is rarely conducted at primary or mental healthcare facilities because of gaps in health care and the stigma of mental illness. This article describes a quality improvement project, conducted at an integrated healthcare primary and mental healthcare facility in the United States. The facility provides primary and mental healthcare services, but physical health screening for patients with SMI was needed to identify their risk of developing health problems, such as cardiovascular disease and diabetes. The aims of the project were to identify potential physical health problems, use evidence-based recommendations to address the risks and improve patient outcomes.