Higher vitamin D level associated with lower risk of total cancer
Japanese study suggests beneficial effects for prevention of cancer in all sites
The benefits of vitamin D in the prevention of skeletal disorders have long been recognised. Now, accumulating evidence suggests that these benefits may extend beyond bone health to several chronic diseases, including cancer.
Vitamin D slows the proliferation of malignant cells and exerts a pro-differentiating effect, so they look more like normal cells and grow and spread more slowly. This is done through the regulation of multiple signalling pathways arresting the cycle of malignant cell development.
The effects of vitamin D include influencing apoptosis or normal cell death; angiogenesis, which involves the formation of new blood vessels; and inflammation.
High levels of sunlight are known to correlate with lower death rates from cancer of the...
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